LDHA and cancer: Moreover, in some reports, it was also highlighted that high mTOR activity could be associated with the presence of metabolic plasticity (higher expression level of alternative metabolic enzymes at tissue level, e.g., simultaneously increased expressions of LDHA, GLS, and carnitine palmitoyltransferase 1A — CPT1A) in breast and other cancers [128, 202, 331–333].