Dolichol kinase (dolk), a key enzyme in the protein glycosylation pathway, can regulate the hindbrain expression of the potassium Shaker-like channel encoded by kcna1a (Meserve et al. 2021), and mutations in dolk have been identified in patients with neuropathological conditions such as seizures (Helander et al. 2013) and autism spectrum disorder (Xiong et al. 2019). The gene discussed is DOLK; the disease is autism spectrum disorder.