Representative examples for four different tumour types of structural MRIs and CEST maps (shown in Fig. 2a) and Z-Spectra (shown in Fig. 2b) show a cystic component present in the IDH-wild-type with reduced signal in the FS CEST maps in the amide and amine ranges (Fig. 2a, IDH-wild-type); minor differences between AB and FS maps in the solid tumour, more evident in IDH-mutant_1p/1qret and in the amine range (Fig. 2a). This evidence concerns the gene IDH1 and neoplasm.