We co-transfected ILK overexpression plasmid and circ_0000515 siRNA into RT4 and RT-112 cells and found that ILK overexpression plasmid could significantly mitigate the inhibiting effects of circ_0000515 depletion on proliferative, migrative and invasive abilities of BC cells (Figure 5K–5N). This evidence concerns the gene ILK and breast cancer.