In humans, mutations in CACNA1S, a gene upregulated in mouse Meox2+/− DRG encoding the L‐type voltage dependent calcium channel, cause types of rare, autosomally inherited periodic paralysis, hypokalemic periodic paralysis type 1 (MIM no. 170400) and susceptibility to thyrotoxic periodic paralysis 1 (MIM no. 188580). The gene discussed is MEOX2; the disease is periodic paralysis.