ERBB2 and gastric adenocarcinoma: In our report, we detected that Her-2 protein expression in all cases was negative and was used to assess the malignant biological behavior and prognosis of conventional gastric adenocarcinoma.[20] Furthermore, β-catenin in all cases was only expressed in the cytoplasm, and the results did not correspond with those of previous studies, demonstrating that β-catenin accumulated in the nucleus, followed by activation of the Wnt/β-catenin signaling pathway.