The associated ocular anomalies were dysversion of the optic disc, hypoplasia of the optic nerve, and downward ectopia of the macula.[4] W Doward reported a patient with PA unilaterally with cataract and IH in the contralateral eye who had an A to T substitution at the invariant −2 site of the 3’ splice site of intron 3 of the PITX2 gene. The gene discussed is PITX2; the disease is isolated hemihyperplasia.