FOXC1 and Axenfeld-Rieger syndrome: In 1977, Awan KJ first described the rare joint occurrence of PA and ARS as Peters-Rieger's syndrome; complicated ocular and systemic anomalies were also mentioned.[4] In the literature, only 3 cases with an anterior segment phenotype between the 2 eyes of a patient with coexisting PA and ARS and pituitary homeobox 2 (PITX2) or forkhead box C1 (FOXC1) mutations have been reported.