In contrast, a patient with decompensated cirrhosis (INR 2.0, bilirubin 3 mg/dL, moderate ascites), AFP of 400 ng/mL, and 3 cm of viable tumor would have a calculated dropout risk of 17% at 3 months, 32% at 6 months, and 59% at 12 months. The gene discussed is AFP; the disease is neoplasm.