MYH6 and chronic kidney disease: When MyHCs were normalized to MyHC‐3 (which is the most immature of the MyHC isoforms) to indicate MyHC profile ratios, similar profiles were noted in both cell types, with the greatest contribution being noted from MyHC‐7 in both CON (P < 0.001) and CKD (P < 0.001) cells, followed by MyHC‐8 in CON myotubes (Figure1).