When gliomas were analyzed in affected individuals using in vivo MRS measurements, no significant differences in ratios of PE/PCho, GPCho/glycerophosphoethanolamine (GPE), or (PCho+GPCho)/(PE+GPE), were detected between individuals with mutIDH1R132H and WT IDH1 glioma.245. This evidence concerns the gene IDH1 and central nervous system cancer.