CRP and Anxiety: Using UK Biobank data to assess the relationship between symptoms of anxiety and concentrations of CRP, as well as genetic variants associated with CRP and IL-6 receptor gene regions, it was found that increased anxiety symptoms were related to higher levels of CRP in a dose-response manner (especially among females), but the MR analysis suggested the opposite to that expected, higher CRP was protective against anxiety (Ye et al., 2021).