Thirty of these have evidence of non-pathogenicity (Table S3): 3 have been found in patients confirmed to have another form of muscular dystrophy, 8 were found in patients with normal or heterozygous carrier levels of DYSF protein and therefore likely do not have dysferlinopathy, 4 are either predicted or proven splicing defects, 11 are found in patients with 2 or more other known pathogenic mutations, and 4 are confirmed as benign by ClinVar. This evidence concerns the gene DYSF and neuromuscular disease caused by qualitative or quantitative defects of dysferlin.