Taken together, the chimeric PDL1-scFv-FC-RE7 protein concentrates and targets the antigen to the tumor as a result of PDL1 specificity and permits the cleavage and release of the CTL epitope such that the tumor becomes coated in the antigenic peptide and can be targeted by preexisting antigen-specific T cells to effectively kill the tumor cells. The gene discussed is CD274; the disease is neoplasm.