TA, a synthetic analog of the amino acid lysine, impedes the proteolytic degradation of fibrin by preventing the attachment of plasminogen and plasmin, and this antifibrinolytic agent can be used as a mouthwash and toothpaste to prevent gingival bleeding, as well as postsurgical bleeding in patients on anticoagulants after oral surgery [34]. The gene discussed is PLG; the disease is Gingival bleeding.