The result of KEGG analysis revealed that DEPPARGs were mainly involved in the PPAR signaling pathway, cholesterol metabolism, ovarian steroidogenesis, platinum drug resistance, and microRNAs in cancer (Supplementary Figure 1(b)), which suggested that DEPPARGs might function as the crucial role in the tumorigenesis, progression, and drug resistance of BLCA. The gene discussed is PPARA; the disease is bladder transitional cell carcinoma.