We found increased mRNA levels of two receptors that activate NF-κB, TLR4 ( + 11%; F(1,151) = 8.15, Cohen’s d = 0.40, p = 0.005, adjusted p = 0.10) and TNFR2 ( + 7%; F(1,154) = 8.21, Cohen’s d = 0.47, p = 0.005, adjusted p = 0.10) in people with schizophrenia compared to controls. The gene discussed is TLR4; the disease is schizophrenia.