In this study, using a larger sample here, we replicated our previous findings of increased IL-1β mRNA in the blood of people with schizophrenia and lack of difference in IL-6, IL-8 and IL-18 mRNAs between controls and patients in an extended clinical sample (43 controls and 43 patients previously versus 83 controls and 87 patients in the current study) [18]. Here, IL18 is linked to schizophrenia.