KLF4 and neoplasm: MiR-135b-5p and GPRC5A were conspicuously decreased in the tumor tissue of miR-135b-5p antagomir+Ad-NC group, and the expression of KLF4 was higher than NC group, while GPRC5A level in the miR-135b-5p antagomir+Ad-GPRC5A group was markedly higher than that in the other 2 groups (Fig. 7C).