SRSF1 regulates the alternative splicing of many other cancer-related genes such as BCLX, MCL1, CASP2, CASP9, CCND1, RPS6KB1, RAC1, RON, MKNK2, etc. which are reported to involve in cell proliferation, apoptosis, or cell cycle progression [46]. This evidence concerns the gene CASP2 and cancer.