Indeed, high expression of AZGP1 was reported in multiple malignancy tumors such as lung cancer and breast cancer, which played a vital role in lipid mobilization and contributed to malignancy-associated cachexia.39,40 And S100A13, a member of the S100 family, was closely associated with aggressive invasive phenotype and angiogenesis.30 Functioning in delivering aminoacylate-tRNA to a site of the ribosome for decoding of mRNA, EEF1A2 played an important role in translation and might also act as an oncogene in lung cancer and pancreatic cancer.41,42. This evidence concerns the gene S100A13 and lung cancer.