Indeed, a previous study has revealed that the TYRO3 and GAS6 may promote the Mφ polarization to the tumor-promoting M2 phenotype,25 while LILRB2 was also related to the in NSCLC can promote the polarization of tumor-infiltrating myeloid cells to the inflammatory phenotype.26 Our results revealed the increased CCI in both LUAD and LUSC and some receptor–ligand parings may play functional roles in NSCLC. This evidence concerns the gene GAS6 and non-small cell lung carcinoma.