For instance, we identified the receptor–ligand parings between tyrosine kinase receptors TYRO3 and GAS6, the immunosuppressive receptor LILRB2 and HLA-F, were specifically occurred in the AT2 cells of LUSC (Fig. 4f), whereas the interaction between AXL and GAS6 was observed in fibroblasts in LUAD but not in their adjacent tissues (Fig. 4g), consistent with their potential functions in NSCLC. This evidence concerns the gene NTRK1 and non-small cell lung carcinoma.