ADCY9 and Alzheimer disease: Additionally, we found DMRs annotated to several genes previously associated with psychiatric disorders including ARID1B, ADCY9, and DIP2A (75-77), as well as MCF2L, and homeobox genes including HOXA3, HOXA4, HOXA5, HOXB7, and MEIS1, which have been reported to be associated with pathology of Alzheimer’s disease (16,78).