Moreover, PrnpZH3/ZH3 mice presented more seizures and blinking episodes per animal than Prnp+/+ individuals (Seizure: PrnpZH3/ZH3 = 2.45 ± 0.74 vs. Prnp+/+ = 1.06 ± 0.83; p = 0.019; Blinking: PrnpZH3/ZH3 = 0.95 ± 0.29 vs. Prnp+/+ = 0.22 ± 0.13; mean ± S.E.M. p = 0.069; Mann-Whitney U non-parametric test) (Fig. 5b). The gene discussed is PRNP; the disease is Seizure.