In FCMD, neurofibrillary tangles (NFTs), intracellular aggregates of phosphorylated tau (p‐tau), are observed in “mature neurons” of elderly patients' brains, particularly around 30 years old,18, 19 whereas senile plaques, as amyloid‐β (Aβ) deposits, are absent.18, 19. Here, MAPT is linked to Senile plaques.