To explore whether the changed gene expression in Brca1-MT epithelial cells has an effect on the function of immune cells, we next performed cytometry by time of flight (CyTOF) analysis to examine myeloid-derived suppressor cells (MDSCs) from tumor tissues with Ctr-545 cells or 545 cells expressing sgATP11b, sgATP11b/OE-Ptdss2, or sgATP11b/sgPtdss2 in nude mice using a combination of antibodies, including anti-CD45, anti-CD11b, anti-Ly6G, and anti-Ly6C. The gene discussed is BRCA1; the disease is neoplasm.