The focus of this review is to examine the HPA axis function and related regulatory neuropeptide (arginine vasopressin [AVP], oxytocin [OT], corticotropin-releasing factor [CRH], serotonin [5-HT], and dopamine [DA]) expression and action as they relate to androgens.7 The role of androgens and ARs in stress-related disorders and potential therapeutic methods are discussed.8 This evidence concerns the gene CRH and stress-related disorder.