Furthermore, the plasma of ovarian cancer patients carried higher levels of exosomal proteins, including melanoma-associated antigen 3/6 (MAGE 3/6) and transforming growth factor β 1 (TGF-β1), than that of ovarian benign tumor patients and healthy individuals, which provided a novel strategy to diagnose ovarian cancer patients.89 This evidence concerns the gene MAGEA3 and ovarian cancer.