In addition, another study revealed that 1,433 proteins and 1,227 lipid species were identified in exosomes from the SKOV3 ovarian cancer cell line and HOSEPiC ovarian surface epithelial cell line, and demonstrated that the lipids cholesterol ester (ChE) and zymosterol (ZyE) species and collagen type V alpha 2 chain (COL5A2) and lipoprotein lipase (LPL) proteins were more abundant in exosomes derived from SKOV3 ovarian cancer cells than those derived from HOSEPiC ovarian surface epithelial cells.97 This evidence concerns the gene COL5A2 and ovarian cancer.