As expected, mice infected by the fbp1Δ zbp1Δ double mutant developed lethal infections by 40 dpi, and four mice infected by the fbp1Δ zbp1Δ double mutant still survived when we terminated the animal study (80 dpi) (Figure 5A), indicating that the zbp1Δ mutation indeed partially rescued the virulence attenuation of the fbp1Δ mutant. The gene discussed is ZBP1; the disease is infection.