In the whole group of patients, multiple stepwise backward regression analysis with PCSK9 as dependent variable and age, apo B100, apo B48, apo A1, apo C3, PTX3, BMI, HbA1c, NAFLD, and statin treatment as independent variables revealed that PTX3, apo B100, apo A1, apo B48, and BMI were positively and presence of NAFLD and HbA1c negatively associated with PCSK9 concentrations (Table 5). The gene discussed is PTX3; the disease is metabolic dysfunction-associated steatotic liver disease.