In the group of patients without NAFLD, multiple stepwise backward regression analysis with PCSK9 as dependent variable and PTX3, apo B48, apo B100, BMI, and apo A1 as independent variables revealed that PTX3, apo B48, and apo A1 were significantly associated with PCSK9. This evidence concerns the gene PTX3 and metabolic dysfunction-associated steatotic liver disease.