SHBG and type 2 diabetes mellitus: The three studies used for the diabetes comparison represent the largest candidate protein characterisations of type 2 diabetes to date and the top markers identified included aminoacylase-1 (ACY-1), sex hormone-binding globulin (SHBG) and growth hormone receptor (GHR) (Elhadad et al., 2020; Gudmundsdottir et al., 2020; Ngo et al., 2021).