To compare our data with a widely used mouse model of COVID-19, we infected KRT18-hACE2 transgenic mice that express human ACE2 under control of the human keratin 18 promoter (McCray et al., 2007; Oladunni et al., 2020) with either 1 × 103 or 1 × 104 TCID50 of BavPat1 and monitored the disease course over 7 days. This evidence concerns the gene ACE2 and COVID-19.