Mutations in RIC-1, a subunit of the Golgi-localized guanine nucleotide exchange factor (GEF) for RAB6A, cause CATIFA (cleft lip, cataract, tooth abnormality, intellectual disability, facial dysmorphism, attention-deficit hyperactivity disorder) syndrome (Unlu et al., 2020). This evidence concerns the gene RIC1 and Intellectual disability.