In terms of cancer, Fan et al. demonstrated that RTL1 could promote melanoma proliferation by regulating the Wnt/β‐catenin signaling pathway43 and Korbut et al. also revealed the Wnt/β‐catenin signaling pathway regulated by Tiam1 could contribute the metastasis of thyroid cancer.44 This evidence concerns the gene TIAM1 and thyroid cancer.