Remarkably, overexpression of netrin‐1 or brain administration of recombinant netrin‐1 is neuro‐protective and neuro‐restorative in mouse and rat models of PD.[12] Therefore, both DCC and UNC5C are implicated in netrin‐1 deficiency‐induced dopaminergic neuronal loss and PD pathologies. Here, UNC5C is linked to Parkinson disease.