Though both UNC5C and DCC contribute to netrin‐1 scarcity‐incurred PD pathogenesis, we find that UNC5C is more important in this effect than DCC, because deletion of UNC5C attenuates α‐Syn pathologies and decreases dopaminergic neuronal loss more robustly than DCC eradication (Figures 5, 6). This evidence concerns the gene UNC5C and Parkinson disease.