TGFB1 and neoplasm: Two stromal genes reported as myofibroblastic markers, Acta1, belonging to the actin family and Actn2, a member of the spectrin superfamily, were strongly linked to the network of myofibroblastic genes and connected with the tumor gene cluster, via TGFB1, TGFB3, HGF,LAMC3 and LAMA5, FIGF and HSPB128,29.