Further, the deletion of chromosome 15q15.3 from STRC to CATSPER2, is also known to be a genetic cause of deafness infertility syndrome (DIS: OMIM 611,102), which is associated with not only hearing loss but also male infertility, as CATSPER2 plays crucial roles in sperm motility15,16. This evidence concerns the gene CATSPER2 and deafness-infertility syndrome.