In this regard, significant differences were observed between nuclear MAGE-A6 expression with age (P = 0.016), tumor size (P = 0.044), different histological grade (P < 0.0001), PT stage (P < 0.0001), LP involvement (P < 0.0001), and L/M involvement (P < 0.0001) in terms of H-score (Table 1). The gene discussed is MAGEA6; the disease is neoplasm.