It is important to note that although ART duration positively correlated with the total duration of HIV infection (Spearman’s rho = 0.58, p = 2.0 × 10−54), the total duration of HIV infection was not associated with CHIP (p = 0.452; paired Mann–Whitney U test on matched CHIP carriers and non-carriers, p = 0.22). Here, STUB1 is linked to HIV infectious disease.