CD274 and chronic myelogenous leukemia, BCR-ABL1 positive: In addition, blocking the PD-1/PD-L1 interaction by PD-L1 or PD-1 antibody together with cytotoxic T cell (CTL) transfer eradicates CML LSCs41,42, indicating that PD-L1 protects CML LSCs from CTL-mediated elimination.