To investigate which specific genes in the positive or negative regulatory SUMOylation pathway were integration sites within the transposon screen, we searched the CISs identified in the A/R/M screen and identified the SUMO protease gene Senp6 as a putative cancer driver gene in 13 out of 48 A/R/M lymphomas (Fig. 2b and Supplementary Data 1). The gene discussed is SENP6; the disease is cancer.