Intriguingly, we previously described23 the core components of the cohesin complex, including RAD21, STAG1, and STAG2 as bona fide SENP6 targets23 (Supplementary Fig. 10a), and now identified the respective genes as putative tumor suppressors in the transposon screen (Supplementary Figs. 10b and 9g). This evidence concerns the gene STAG2 and neoplasm.