Among the 41 significantly enriched pathways were several pathways with well-defined roles in cancer and lymphomagenesis, including the “VEGFA-VEGFR2” pathway and the “Antigen activates B-cell Receptor (BCR) leading to generation of second messengers” pathway (Fig. 2a; full list of enriched pathways, Supplementary Data 3). The gene discussed is KDR; the disease is cancer.