DARS1 and viral infectious disease: Analysis of the DARs with decreased accessibility for localization to nearest genes and for gene ontology (GO) with ClusterProfiler (19) demonstrated associations with GO BIOLOGICAL PROCESSES of (i) cell polarity, axonogenesis, and actin filament organization in DU-145 cells (Fig. 2B) and (ii) regulation of the type I IFN pathway and response to viral infection in BT-549 cells (Fig. 2C).