Thus, targeting the identified neutrophil/Gas6/AXL axis might also be of relevance for cancers with a high prevalence to spread to the liver, such as CRC, melanoma, breast and lung.39 In summary, our findings are important and timely as they could help improve in the near future the design of treatment regimens for patients with cancer with liver metastases. Here, AXL is linked to colorectal carcinoma.