In mechanism, ALKBH5 is linked to 3’-UTR of protein kinase CK2α, reduces CK2α in m6A dependent manner, influences the relative half-life thus affects its stability, regulates the glycolysis pathway and inhibits CK2α mediated glucose absorption, lactate and ATP production, thus inhibits the progress of bladder cells and promotes the sensitivity of cancer cells to cisplatin [128]. This evidence concerns the gene ALKBH5 and cancer.