ACVRL1 and keratoconus: Characterization of Fcgr1-CrexAcvrl1fl/fl mice using our defined panel readily demonstrates the cruciality of the ALK1-BMP9/10 axis in KC development emphasizing that mac-stromal-cell cross-talk goes much further than the exchange of growth factors (Guilliams et al., 2020; Zhou et al., 2018).