Simultaneous activation of B cells with the cancer-associated antigen Folate Receptor alpha (FOLR) together with IL-17+BAFF+CpG also allowed the detection of secreted antibodies recognizing FOLR-expressing cells (IGROV1) in individual B-cell cultures from two of the three healthy volunteers tested (IGROV1 cancer cell-based ELISA, Fig. 4G). Here, FOLR1 is linked to cancer.