For example, tumour cell CD47 and CD24 engage cognate receptors on TAMs, signal regulatory protein-α (SIRPα) and sialic acid-binding Ig-like lectin 10 (Siglec-10), respectively, to trigger signalling cascades which inhibit macrophage phagocytosis [102, 103] (Figure 3). This evidence concerns the gene CD24 and neoplasm.