Age category, sex, marital status, residence, educational status, occupation, disclosure status, Baseline WHO clinical stage, baseline CD4 cell count, functional status at enrolment, level of adherence, undernutrition, serum creatinine, serum ALT, past TB history, TB treatment, cotrimoxazole prophylaxis, isoniazid prophylaxis and recent viral load were eligible for multivariable analysis. The gene discussed is CD4; the disease is tuberculosis.