GSK3B and X-linked adrenoleukodystrophy: Aberrant activity of GSK3β has also been linked to peroxisomal disorders; GSK3β activity was increased in the nervous system of mouse models for adrenoleukodystrophy and rhizomelic chondrodysplasia punctata and in patient fibroblasts (da Silva et al., 2014; Ranea-Robles et al., 2018).