SIRT3 and diffuse large B-cell lymphoma: SIRT3 mediates proliferation and survival in DLBCL by driving glutamine into the TCA cycle through enhanced GDH activity, which in turn leads to increased production of metabolic precursors such as acetyl-CoA (AcCoA) and prevents destructive autophagy—thus delineating a crucial SIRT3–GDH–TCA cycle–autophagy pathway (9).