ADIPOQ and medullary thyroid gland carcinoma: Nevertheless, this correlation with low serum levels of the adipokine was not found in medullary thyroid cancer [182]. In endocrine malignances it was reported that adiponectin may be able to suppress several important processes leading to metastatization, including adhesion, invasion and migration of, for instance, breast cancer cells [183]. The reduction of cancer cell migration and invasion by adiponectin at least in part occurs through the AMPK/Akt pathway [184].