Moreover, in the publication with eloquent title “When two pandemics meet: why is obesity associated with increased COVID mortality?” special emphasis is given on the role of significantly decreased circulation levels of adiponectin in obese patients which facilitates an exaggerated inflammatory response in the capillaries of the lungs and negatively affects survival in this cohort of ‘double pandemic’ patients [188]. Here, ADIPOQ is linked to obesity due to melanocortin 4 receptor deficiency.