IL‐17A is another important effector cytokine of ILC3s, and protects the host from various infections including UPEC.[33, 36, 53, 54] Interestingly, the IL‐17 receptor was highly expressed in the bladder, whereas the expression of the IL‐22 receptor was primarily enriched in the gut tissue (Figure 7C). The gene discussed is IL17A; the disease is infection.