SLC9A1 and Stroke: In addition to stimulated microglial stripping of the damaged dendritic spines in the acute post-stroke Nhe1 cKO brains, we also detected enhanced spine remodeling at the chronic stage of 28-day post-stroke, reflected by the increased number of dendritic branching, as well as a higher dendritic spine density and restored spine morphology, which was positively correlated with the improved cognitive memory functions in these cKO mice (Supplementary Figure 10).