In assessment of oligodendrogenesis and cell death, quantification of OPC counts (NG2+Olig2+), proliferative OLs (Ki67+Olig2+), and apoptotic OLs (Caspase3+Olig2+) were conducted at baseline (naïve, Supplementary Fig. 7d), and 3–28-day post-stroke in the CC of WT and cKO brains (Fig. 7a–c). This evidence concerns the gene MKI67 and stroke disorder.